Symmetry and symmetry breaking in cancer: a foundational approach to the cancer problem
نویسندگان
چکیده
Symmetry and symmetry breaking concepts from physics and biology are applied to the problem of cancer. Three categories of symmetry breaking in cancer are examined: combinatorial, geometric, and functional. Within these categories, symmetry breaking is examined for relevant cancer features, including epithelial-mesenchymal transition (EMT); tumor heterogeneity; tensegrity; fractal geometric and information structure; functional interaction networks; and network stabilizability and attack tolerance. The new cancer symmetry concepts are relevant to homeostasis loss in cancer and to its origin, spread, treatment and resistance. Symmetry and symmetry breaking could provide a new way of thinking and a pathway to a solution of the cancer problem.
منابع مشابه
A Computational Study to Find the Vibrational Modes Connected with Specific Molecular Structures of Calculated Compound
The purpose of this research is to provide a deeper understanding of the planar high- symmetry configuration instability. In the ideal case, the distortion corresponds to the movements of nuclei along normal modes that belong to non-totally symmetric irreps of the high symmertry (HS) point group of molecule. The analysis of the structural distortion from the HS nuclear arrangements of the JT ac...
متن کاملAnalysis of the Effects of Hyperthermia with Magnetic Nanoparticles on Cancer Tissues
Introduction: Hyperthermia is one of the noninvasive methods of treating cancer. In this method, heat can be generated in several methods. One of these methods is injecting magnetic nanoparticles as a solution into the tumor site and place it in a magnetic field. Methods: The study was analytical one, modeling was performed using computational methods, and in vitro experimental data were used ...
متن کاملنقش شکست تقارن بار در اختلاف انرژی بستگی هستههای آینهای 15O-15N و 17F-17O
Charge symmetry breaking potentials due to the exchange of pseudoscalar and vector mesons in mirror nuclei are considered. With the computation of coulmb energy along with the present charge symmetry breaking effects provide a reasonably accurate description of the binding energy differences between mirror nuclei.
متن کاملNoether Symmetry in f(T) Theory at the anisotropic universe
As it is well known, symmetry plays a crucial role in the theoretical physics. On other hand, the Noether symmetry is a useful procedure to select models motivated at a fundamental level, and to discover the exact solution to the given lagrangian. In this work, Noether symmetry in f(T) theory on a spatially homogeneous and anisotropic Bianchi type I universe is considered. We discuss the Lagran...
متن کاملNumerical Simulation of Free Surface Flows and Comparison of Symmetry and Real Boundary Conditions at the Free Surface
For implementation
 of the free surface boundary condition, a new subroutine has been introduced to an existing steady 3-D body fitted code. This code was previously written for steady flow simulation in closed ducts. The algorithm used in this subroutine reduces the instability problem according to the free surface wave generation. For code validation, it was applied to two different open c...
متن کامل